Saturday, June 27, 2020

Why does the new corona virus make some patients more  sicker?



The new corona virus makes some people very sick, while there are many who are not affected, but why?

This is a question that is being researched by medical experts around the world.Now, a new study is likely to answer that, after a genetic analysis of Code 19 patients, it has been suggested that blood groups may also play a role in exacerbating the disease.
After comparing the genes of thousands of patients in Europe during the study, it was found that patients with blood group A were more likely to have severe seizures, while those with blood group O had a lower risk.

 
Preliminary results of the study were released earlier this month, but are now being published in the New England Journal of Medicine, a leading medical journal, which will not prove blood type, but in March in China. The results of a recent study were confirmed, with similar findings.

The study involved scientists from Italy, Spain, Denmark, Germany and other European countries, who compared the 2,000 most critically ill people with code 19 to thousands of people with mild to severe symptoms. Were The researchers linked 6 gene types to the serious disease, some of which could affect people with the virus, while blood groups were linked to potential risk.
There are 4 main blood groups A, B, AB and O, which are determined by the proteins present on the surface of red blood cells.

Researchers say that people with the O group are better at identifying specific proteins, which gives them some protection.
The results, released earlier this month, found two sites in the human genome that increased the risk of respiratory failure in people with code 19, one of which was in a gene that is linked to blood groups. Determines
According to research, people with A blood group who have code 19 may be more likely to need oxygen or a ventilator. However, Andre Frank, a professor of molecular medicine at the University of Kyle in Germany, who was involved in the study, said that it was not necessary for a blood group to determine a person's illness.
"Until now, we have not been able to differentiate between blood groups or certain genetic factors linked to blood group," he said. Individuals are 50% more secure and those in Group A are 50% more at risk. This month, preliminary research by biotechnology company 23 & May found that people with the O-blood group had a lower risk of contracting the new Novel Corona virus. According to the results, people with O-blood group are 9 to 18 percent less likely to be diagnosed with corona virus than others.

Research has shown that people who are at higher risk of contracting the virus, such as medical personnel and those engaged in urgent work, or those who are in contact with an infected person, have an increased risk of developing the virus in O-blood group 13. Less than 26%.
The research team did not find any significant difference in the risk of other blood groups, but did say that people with O-blood group are less likely to be hospitalized.
Work on the study began in April and the volunteers involved in the survey were asked to answer questions such as whether they had symptoms such as the flu or the common cold and when they were diagnosed, treated or as a result of code 19. I didn't have to go to the hospital.
The genetic information of these volunteers was also obtained.
Preliminary results showed that the ABO gene, which determines different blood groups, reduces the risk of being diagnosed with the disease.
The total number of patients with O blood group was 1.3%, while the number of patients with A blood group was 1.4 and the number of patients with B and AB blood groups was 1.5%. When the researchers looked at people who were at higher risk of contracting the virus, they found that the chances of being diagnosed with code 19 in O-blood group were 3.2% lower than in others. It was 4% in group and 4.1% in AB blood group. But a statement from the company acknowledged that research was still in its infancy.

Similarly, a March study in China found that people with blood type A had a higher risk of developing code 19, while people with blood type O had a significantly lower risk. ۔
The researchers said that the difference in the risk of different blood groups and code 19 may be the result of specific antibodies in the blood, but more research is needed to confirm this Other medical experts, citing new research, say the work is limited and the research team did not consider a number of other factors that increase the risk of code 19 in an individual.

He said that researchers should consider other factors in order to understand why the blood group does not provide adequate protection against the disease.
"Everyone needs to be very careful about the corona virus, regardless of their blood type," he said. But nowhere is it said that people with O-blood group have 100% protection against this disease or people with A-blood group are 100 percent at risk.

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